Antibody Sequencing and Application Platform

KMD Bioscience has deep knowledge base of antibody development, and our R&D team can provide comprehensive antibody downstream engineering services, including antibody purification, antibody pairing (ELISA custom development), antibody & antigen binding kinetics studies, antibody sequencing and antibodies modification services, etc.

 

Antibody Purification Service

KMD Bioscience mainly uses two methods to purify antibodies for scientists: Protein A/G affinity purification and antigen-based purification. At the same time, we can also provide other antibody purification protocols, such as chicken IgY antibody purification.

 

Antibody Pairing (ELISA Custom Development)

Antibody pairing is critical for the development of ELISA kits. Our antibody team members have extensive experience in developing clinical assays and can provide comprehensive enzyme-linked immunoassay kit development services, including detection sensitivity verification, linear range Verification, repeatability verification, specificity verification and thermal stability (37 °C or 25 °C thermal stability) verification. We have successfully developed a small molecule detection kit with a detection sensitivity of 0.1 ppb.

 

Antibody and Antigen Binding Kinetics Study

We are able to provide BIAcore-based antibody affinity testing services for the development of vaccine assays that can be used to assess the immunogenicity of antigens in animals in vitro. At the same time, it can solve the problem of difficulty in selecting different antibodies against the same antigen in the process of vaccine development and the determination of antibody affinity in the rapid detection method.

 

Antibody Sequencing Service

KMD Bioscience uses the most advanced Orbitrap Fusion Lumos mass spectrometer and powerful antibody sequencing data processing software, combined with gene sequencing and bioinformatics database, and established a new generation of antibody sequencing platform to achieve fast and accurate analysis of antibody primary structure, thus ensuring the accuracy of an antibody sequencing. KMD Bioscience is able to provide customers with antibody sequencing services for all species.

 

Antibody Modification

Immunological testing usually involves the modification of antibodies. Our scientists can provide high-quality antibody labeling services, including fluorescent molecular markers (FITC, FAM, etc.), vector coupling (agarose beads, magnetic bead coupling, etc. ) and enzyme labeling (HRP, AP, etc.).