IOS RNAi Stable Cell Line Services

Integrating exogenous plasmid DNA into the chromosome of host cells, and then express the target protein for a long time, which is called stable cell line. High-quality stable cell line plays an important role in biological research, including drug development, gene function research and recombinant antibody production. However, constructing an effective cell line is a complex and time-consuming task. KMD Bioscience has rich experience in stable cell line construction, our cell lines can be directly applied to downstream biological research. We have successfully constructed a large number of target cell lines for many clients so far. Based on advanced technology and dedicated research teams, KMD Bioscience can provide the following services:

 

CRISPR/Cas9 Knock-out Cell Line Services

IOS Overexpression Stable Cell Line Services

IOS RNAi Stable Cell Line Services

Pinpoint Targeted Integration Cell Line Services

 

IOS RNAi Stable Cell Line Construction

KMD Bioscience can provide RNAi stable cell line services based on our patented IOS (Integration Operating System) recombination technology. Using this technology, the target shRNA was integrated into the genomic high expression sites. These sites are not only safe (no gene), but also have higher gene expression level (active expression sites), so that shRNA can be transcribed and expressed at a high level, then interfering the target gene and stably inherited for a long time. In addition, we can also provide transient expression services.

 

Service Procedure:

 

Service Highlights:

*We customize our offering to meet your specific project needs and provide experienced scientific support every step of the way.

*Pinpoint targeted integration rather than random integration.

*Multiple genes can be inhibited simultaneously.

*Stable inheritance, the gene will not be lost in the process of passage.