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Anti-Human APP Abeta Recombinant Antibody(Bapineuzumab)

Product Information
Catalog Number YR1164
Product Name Anti-Human APP Abeta Recombinant Antibody(Bapineuzumab)
Molecular Name Bapineuzumab
Alias Anti-APP Abeta Recombinant Antibody, Research Grade Bapineuzumab
CAS Number 648895-38-9
Target APP Abeta[Homo sapiens]
Isotype IgG1
Clonity Monoclonal
Host Mouse
Source CHO Cells
Size 1mg, 5mg
Concentration 1mg/ml
Purity >95% as determined by SDS-PAGE
Applications WB, FuncS, IF, Neut, ELISA, FCM, IP
Buffer PBS, pH7.5
Background Bapineuzumab (nicknamed "bapi") is a humanized monoclonal antibody that acts on the nervous system and may have potential therapeutic value for the treatment of Alzheimer's disease and possibly glaucoma. However, in 2012 it failed to produce significant cognitive improvements in patients in two major trials, despite lowering key biomarkers of AD, amyloid brain plaque and hyperphosphorylated tau protein in CSF.
Storage It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.