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Catalog Number | YR1164 |
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Product Name | Anti-Human APP Abeta Recombinant Antibody(Bapineuzumab) |
Molecular Name | Bapineuzumab |
Alias | Anti-APP Abeta Recombinant Antibody, Research Grade Bapineuzumab |
CAS Number | 648895-38-9 |
Target | APP Abeta[Homo sapiens] |
Isotype | IgG1 |
Clonity | Monoclonal |
Host | Mouse |
Source | CHO Cells |
Size | 1mg, 5mg |
Concentration | 1mg/ml |
Purity | >95% as determined by SDS-PAGE |
Applications | WB, FuncS, IF, Neut, ELISA, FCM, IP |
Buffer | PBS, pH7.5 |
Background | Bapineuzumab (nicknamed "bapi") is a humanized monoclonal antibody that acts on the nervous system and may have potential therapeutic value for the treatment of Alzheimer's disease and possibly glaucoma. However, in 2012 it failed to produce significant cognitive improvements in patients in two major trials, despite lowering key biomarkers of AD, amyloid brain plaque and hyperphosphorylated tau protein in CSF. |
Storage | It is recommended to aliquote and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |