Monoclonal Antibody Development Service

KMD Bioscience can provide two monoclonal antibody production protocols to meet clients' different needs:

1. Cell fusion technique: including mouse hybridomas, mouse/rat, mouse/guinea pig cell fusion, and fully humanized hybridoma to produce monoclonal antibodies.

2. Phage display library construction technique. We can provide antigen design, peptide synthesis, gene expression, immunization, antibody purification, identification and antibody labeling services with our well-established and powerful Antibody Engineering Platform.

 

Monoclonal antibodies produced by cell fusion

Monoclonal antibody production by cell fusion technique, the hybridoma is resulting from the fusion of B lymphocytes and myeloma cells. The antibody secreted from hybridomas can only react with certain antigenic determinant, therefore, it is provided with high specificity and high titer. Monoclonal antibodies are widely used in biological and medical research. We accept small molecules, peptides, modified peptides, proteins, fusion proteins, modified proteins, etc. used as antigens for monoclonal antibody production.

 

Monoclonal antibodies produced by phage display technology 

KMD Bioscience utilizes phage antibody library technology to provide monoclonal antibody customization of various species, such as human, mouse, rabbit, chicken, sheep, goose, pig, cow, horse, donkey, camel, alpaca, etc. 

By using our M13 filamentous phage display technique, KMD Bioscience is able to construct natural or immunogenic antibody phage display libraries of different species for clients and the library capacity is up to 1011 . At present, we have established and optimized our platform. Through phage antibody display technology, we can provide recombinant monoclonal antibody production and corresponding services for many species.