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Catalog Number | KMH1029 |
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Product Name | Recombinant Human EPHA1 Protein, His Tag |
Product Description | Recombinant Human EPHA1 Protein, His Tag (KMH1029) contains the human EPHA1(Lys26-Glu547) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | EPHA1 |
Uniprot ID | P21709 |
Alias | EPH, EPHT, EPHT1, EPH receptor A1 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 57.53 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Epha1 is a member of the Eph family of receptor tyrosine kinases that have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the Eph subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. EPHA1 seems to be a marker of the differentiated normal epidermis and its downregulation in nonmelanoma skin cancer may contribute to carcinogenesis of these very frequent human tumors. EPHA1 represents a new potential prognostic marker and therapeutic target in nonmelanoma skin cancer. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |