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Determining Seroconversion to Peste Des Petits Ruminants Virus
2023-10-12 Read(275)

Peste des petits ruminants (PPR) is an infectious viral disease, primarily of small ruminants such as sheep and goats, but is also known to infect a wide range of wild and domestic Artiodactyls inc...
Assessing the Generation of Tissue Resident Memory T Cells by Vaccines
2023-09-28 Read(204)

Vaccines have been a hugely successful public health intervention, virtually eliminating many once common diseases of childhood. However, they have had less success in controlling endemic pathogens...
Antiviral Neutralizing Antibodies: From in Vitro to in Vivo Activity
2023-09-25 Read(172)

Neutralizing antibodies (nAbs) are being increasingly used as passive antiviral reagents in prophylactic and therapeutic modalities and to guide viral vaccine design.
The Unique Properties of IgG4 and its Roles in Health and Disease
2023-09-21 Read(208)

IgG4 is the least abundant subclass of IgG in human serum and has unique functional features. IgG4 is largely unable to activate antibody-dependent immune effector responses and, furthermore, under...
Cell Death by Phagocytosis
2023-09-18 Read(178)

Cells can die as a consequence of being phagocytosed by other cells — a form of cell death that has been called phagotrophy, cell cannibalism, programmed cell removal and primary phagocytosis. How...
Native Mass Spectrometry Combined with Enzymatic Dissection Unravels Glycoform Heterogeneity of Biopharmaceuticals
2023-09-07 Read(173)

Robust manufacturing processes resulting in consistent glycosylation are critical for the efficacy and safety of biopharmaceuticals.
Trogocytosis Challenges the Cellular Specificity of Lineage Markers and Monoclonal Antibodies
2023-08-31 Read(147)

The transfer of surface molecules between cells by trogocytosis challenges the concept of cell type-unique surface markers and indicates that monoclonal antibodies used for therapeutic purposes may...
CLASH:Large-scale Engineering System for the Discovery of Better CAR T Cells
2023-08-29 Read(209)

Adoptive immune cell therapy has been effective in treating haematological cancers. However, some patients experience disease relapse, which may be attributed to insufficient persistence of T cells...
Commensal Fungi Support Granulocyte Development
2023-08-24 Read(190)

Laboratory mice kept in specific-pathogen-free (SPF) conditions are routinely used to dissect the immune system, but they lack the microbial exposures that normally shape the immune system.
Lactation-associated Macrophages
2023-08-22 Read(185)

Macrophages contribute to mammary gland remodelling during development, pregnancy and involution postlactation, but less is known about their role during lactation.
Cell Signaling in Cancer: From Mechanisms to Therapy
2023-08-17 Read(189)

Since 2016, this conference has brought together investigators focused on basic mechanisms of cancer development, translational research, and early-phase clinical research.
Image-seq: Image-guided Cell Isolation for Spatially Resolved Transcriptomic Analysis
2023-08-15 Read(263)

Spatial transcriptomics encompasses a set of technologies capable of resolving spatial differences in gene expression with subcellular resolution.
The Role of Platelets in Immune-mediated Inflammatory Diseases
2023-08-12 Read(247)

Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and uncontrolled inflammation and thrombosis, both of which are responsible for organ damage, morbidity and death.
How to Predict the Specificity of T Cells?
2023-08-07 Read(252)

Recent advances in machine learning and experimental biology have offered breakthrough solutions to problems such as protein structure prediction that were long thought to be intractable.
The Role of Galectins in Immunity and Infection
2023-08-03 Read(184)

The galectin family consists of carbohydrate (glycan) binding proteins that are expressed by a wide variety of cells and bind to galactose-containing glycans.
Laws and Regulations
2022-11-24 Read(178)

Honorary qualification and registered trademark of the company
Mirusviruses Link Herpesviruses to Giant Viruses
2023-04-21 Read(293)

DNA viruses have a major influence on the ecology and evolution of cellular organisms, but their overall diversity and evolutionary trajectories remain elusive. Here we carried out a phylogeny-guid...
The roles of extracellular vesicles in the immune system
2023-04-17 Read(347)

The twenty-first century has witnessed major developments in the field of extracellular vesicle (EV) research, including significant steps towards defining standard criteria for the separation and ...
Role of Unfolded Protein
2023-03-03 Read(367)

Initiating and maintaining optimal immune responses requires high levels of protein synthesis, folding, modification and trafficking in leukocytes, which are processes orchestrated by the endoplasm...
The biology of TREM receptors
2023-02-13 Read(426)

Triggering receptors expressed on myeloid cells (TREMs) encompass a family of cell-surface receptors chiefly expressed by granulocytes, monocytes and tissue macrophages.

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