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Catalog Number | KMH1074 |
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Product Name | Recombinant Human FCER2/CD23 Protein, His Tag |
Product Description | Recombinant Human FCER2/CD23 Protein, His Tag (KMH1074) contains the human FCER2(Asp48-Ser321) was fused with the N-terminus His Tag and expressed in Mammalian cells. |
Molecular Name | FCER2 |
Uniprot ID | P06734 |
Alias | CD23, FCE2, CD23A, IGEBF, CLEC4J, BLAST 2, Fc fragment of IgE receptor II |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 30.14 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | FCER2, the lowaffinity receptor for IgE, belongs to the C-type lectin structural family andplays a role in the regulation of IgE synthesis and IgE mediated activities.It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound FCER2. Thepredominant soluble form of FCER2 (sCD23) consists of 172 amino acidscorresponding to the extracellular domain of the full length precursor.sCD23, in addition to binding IgE, also exerts a number of IgE independentactivities, such as promoting the activation and differentiation of B-cellsand stimulating the release of pro-inflammatory cytokines from monocytes. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |