Recombinant Human IDE Protein, His Tag

Product Information

Catalog Number	KMH1240
Product Name	Recombinant Human IDE Protein, His Tag
Product Description	Recombinant Human IDE Protein, His Tag (KMH1240) contains the human IDE(Met42-Leu1019) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name	IDE
Uniprot ID	P14735
Alias	INSULYSIN, insulin degrading enzyme
Protein Family	Other protein
Size	50ug, 100ug
Species	Human
Host	Mammalian cells
Molecular Weight	107.58 kDa
Purity	≥90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity	No cross-reactivity with other antigens or proteins.
Buffer	PBS
Purification	Affinity Purification
Background	Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently. This discovery revealed considerable amino acid sequence homology between IDE and the previously characterized bacterial protease pitrilysin, suggesting a common proteolytic mechanism.
Storage	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.

Cat#	Product Name	Species	Host	Applications	Size	Price
PA9985	Rabbit Anti-Human IDE pAb	Human	Rabbit		50μl, 100μl	Inquiry
MA293	Rabbit Anti-Human IDE mAb	Human	Rabbit		50μl, 100μl	Inquiry