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Catalog Number | KMH131 |
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Product Name | Recombinant Human IL19 Protein, His Tag |
Product Description | Recombinant Human IL19 Protein, His Tag (KMH131) contains the human IL19(Met1-Ala177) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | IL19 |
Uniprot ID | Q9UHD0 |
Alias | MDA1, NG.1, ZMDA1, IL 10C, interleukin 19 |
Protein Family | Interleukin |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 19.58 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | IL19 is a cytokine that belongs to the IL1 cytokine subfamily. IL-19 is found to be preferentially expressed in monocytes. It can bind the IL2 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |