KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMH1373 |
|---|---|
| Product Name | Recombinant Human MAN1B1 Protein, His Tag |
| Product Description | Recombinant Human MAN1B1 Protein, His Tag (KMH1373) contains the human MAN1B1(Asp106-Ala699) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | MAN1B1 |
| Uniprot ID | Q9UKM7 |
| Alias | MRT15, ERMAN1, ERManI, MANA ER, mannosidase alpha class 1B member 1 |
| Protein Family | Other protein |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 65.34 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | Endoplasmic Reticulum Mannosyl-Oligosaccharide 1, 2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
