Service Line:+1-315-239-3085
Address:FL-4, Building A5, International Enterprise Community, Tianjin, China
Email:info@kmdbioscience.com
Catalog Number | KMH1379 |
---|---|
Product Name | Recombinant Human MAPT/TAU-F Protein, No Tag |
Product Description | Recombinant Human MAPT/TAU-F Protein, No Tag (KMH1379) contains the human MAPT(Met1-Tyr441) was fused without Tag and expressed in E. coli. |
Molecular Name | MAPT |
Uniprot ID | P10636 |
Alias | TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP 17, PPP1R103, microtubule associated protein tau |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | E. coli |
Molecular Weight | 48.51 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | Please contact our customer service for more information. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Tau-352 or Tau-A is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules. Deposits of Alzheimer"s disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as, β-amyloid precursor protein (βAPP), ubiquitin, and various chaperones and protein kinases are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |