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Recombinant Human MAPT/TAU-F Protein, No Tag

Product Information
Catalog Number KMH1379
Product Name Recombinant Human MAPT/TAU-F Protein, No Tag
Product Description Recombinant Human MAPT/TAU-F Protein, No Tag (KMH1379) contains the human MAPT(Met1-Tyr441) was fused without Tag and expressed in E. coli.
Molecular Name MAPT
Uniprot ID P10636
Alias TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP 17, PPP1R103, microtubule associated protein tau
Protein Family Other protein
Size 50ug, 100ug
Species Human
Host E. coli
Molecular Weight 48.51 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin Please contact our customer service for more information.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background Tau-352 or Tau-A is a member of the Tau family of proteins which function to stabilize the microtubules by binding to them. Tau proteins are subject to phosphorylation and this phenomenon regulates the association of the Tau protein with the microtubules. Deposits of Alzheimer"s disease AD-associated proteins, such as hyperphosphorylated Tau, as well as other shared misfolded proteins, such as, β-amyloid precursor protein (βAPP), ubiquitin, and various chaperones and protein kinases are thought to play a pathologic role in the cognitive decline and muscular failure. Malfunctioning of Tau proteins is associated with microtubules disintegration and collapsing of the neuronal transport system.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.