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Catalog Number | KMH1436 |
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Product Name | Recombinant Human NDPKA/NME1 Protein, His Tag |
Product Description | Recombinant Human NDPKA/NME1 Protein, His Tag (KMH1436) contains the human NME1(Met1-Glu152) was fused with the N-terminal His Tag and expressed in E. coli. |
Molecular Name | NME1 |
Uniprot ID | P15531 |
Alias | NB, AWD, NBS, GAAD, NDKA, NM23, NDPKA, NDPK A, NM23 H1, NME/NM23 nucleoside diphosphate kinase 1 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | E. coli |
Molecular Weight | 16.72 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | Please contact our customer service for more information. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |