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Catalog Number | KMH1460 |
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Product Name | Recombinant Human NLGN1 Protein, His Tag |
Product Description | Recombinant Human NLGN1 Protein, His Tag (KMH1460) contains the human NLGN1(Gln46-Val695) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | NLGN1 |
Uniprot ID | Q8N2Q7 |
Alias | NL1, neuroligin 1 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 71.5 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Neuroligin-1, also known as NLGN1, is a single-pass type I membrane protein which belongs to the type-B carboxylesterase/lipase family. Neuroligins are cell-adhesion molecules located at the postsynaptic side of the synapse. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Neurexins and neuroligins are cell adhesion molecules present in excitatory and inhibitory synapses, and they are required for correct neuron network function. These proteins are found at the presynaptic and postsynaptic membranes. Neurexins and neurologins have an essential role in synaptic transmission. Altered neuronal connections during the development of the human nervous system could constitute the basis of the etiology of numerous cases of autism spectrum disorders. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |