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Recombinant Human NLGN1 Protein, His Tag

Product Information
Catalog Number KMH1460
Product Name Recombinant Human NLGN1 Protein, His Tag
Product Description Recombinant Human NLGN1 Protein, His Tag (KMH1460) contains the human NLGN1(Gln46-Val695) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name NLGN1
Uniprot ID Q8N2Q7
Alias NL1, neuroligin 1
Protein Family Other protein
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 71.5 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background Neuroligin-1, also known as NLGN1, is a single-pass type I membrane protein which belongs to the type-B carboxylesterase/lipase family. Neuroligins are cell-adhesion molecules located at the postsynaptic side of the synapse. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Neurexins and neuroligins are cell adhesion molecules present in excitatory and inhibitory synapses, and they are required for correct neuron network function. These proteins are found at the presynaptic and postsynaptic membranes. Neurexins and neurologins have an essential role in synaptic transmission. Altered neuronal connections during the development of the human nervous system could constitute the basis of the etiology of numerous cases of autism spectrum disorders.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.