Recombinant Human PFKFB1 Protein, His Tag

Product Information

Catalog Number	KMH1545
Product Name	Recombinant Human PFKFB1 Protein, His Tag
Product Description	Recombinant Human PFKFB1 Protein, His Tag (KMH1545) contains the human PFKFB1(Ser2-Tyr471) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name	PFKFB1
Uniprot ID	P16118
Alias	F6PK, HL2K, PFRX, 6 phosphofructo 2 kinase/fructose 2, 6 biphosphatase 1
Protein Family	Other protein
Size	50ug, 100ug
Species	Human
Host	Mammalian cells
Molecular Weight	51.7 kDa
Purity	≥90% as determined by SDS-PAGE
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity	No cross-reactivity with other antigens or proteins.
Buffer	PBS
Purification	Affinity Purification
Background	PFKFB1 is a member of the family of bifunctional 6-phosphofructo-2-kinase: fructose-2, 6-biphosphatase enzymes which forms a homodimer that catalyzes both the synthesis and degradation of fructose-2, 6-biphosphate using independent catalytic domains. Fructose-2, 6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Regulation of fructose-2, 6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Storage	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.

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