Recombinant Human RHEB Protein, Gst Tag

Product Information

Catalog Number	KMH1644
Product Name	Recombinant Human RHEB Protein, Gst Tag
Product Description	Recombinant Human RHEB Protein, Gst Tag (KMH1644) contains the human RHEB(Met1-Met184) was fused with the N-terminal Gst Tag and expressed in E. coli.
Molecular Name	RHEB
Uniprot ID	Q15382
Alias	RHEB2, Ras homolog, mTORC1 binding
Protein Family	Other protein
Size	50ug, 100ug
Species	Human
Host	E. coli
Molecular Weight	46.24 kDa
Purity	≥90% as determined by SDS-PAGE
Endotoxin	Please contact our customer service for more information.
Cross-Reactivity	No cross-reactivity with other antigens or proteins.
Buffer	PBS
Purification	Affinity Purification
Background	RHEB is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is vital in the regulation of growth and cell cycle progression. RHEB has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form. Drosophila RHEB is a direct target of Tsc2 GTPase-activating protein (GAP) activity both in vivo and in vitro. Point mutations in the Drosophila RHEB gene inhibits cell growth while overexpression promotes cell growth. RHEB functions downstream of Tsc1 and Tsc2 in the mTOR signaling pathway.
Storage	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.

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