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Catalog Number | KMH171 |
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Product Name | Recombinant Human CD16A/FCGR3A Protein, His Tag |
Product Description | Recombinant Human CD16A/FCGR3A Protein, His Tag (KMH171) contains the human FCGR3A(Met1-Gln208) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | FCGR3A |
Uniprot ID | P08637 |
Alias | CD16, FCG3, CD16A, FCGR3, IGFR3, IMD20, FCR 10, FCRIII, FCGRIII, FCRIIIA, FCGR3A, Fc fragment of IgG receptor IIIa |
Protein Family | CD molecule |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 22.99 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Receptors for the Fc region of immunoglobin G (Fcγ R) are divided into three classes and CD16 (Fcγ RIII) is a multifunctional, low/intermediate affinity receptor. In human, CD16 is expressed as two distinct forms (CD16a and CD16b) encoded by two different highly homologous genes in a cell type-specific manner. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. CD16a has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |