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Catalog Number | KMH1713 |
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Product Name | Recombinant Human SH2D1A Protein, His Tag |
Product Description | Recombinant Human SH2D1A Protein, His Tag (KMH1713) contains the human SH2D1A(Met1-Pro128) was fused with the N-terminal His Tag and expressed in E. coli. |
Molecular Name | SH2D1A |
Uniprot ID | O60880 |
Alias | LYP, SAP, XLP, DSHP, EBVS, IMD5, XLPD, MTCP1, XLPD1, SAP/SH2D1A, SH2 domain containing 1A |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | E. coli |
Molecular Weight | 14.08 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | Please contact our customer service for more information. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |