KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMH186 |
|---|---|
| Product Name | Recombinant Human CD31 Protein, His Tag |
| Product Description | Recombinant Human CD31 Protein, His Tag (KMH186) contains the human PECAM1(Met1-Lys601) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | PECAM1 |
| Uniprot ID | P16284 |
| Alias | CD31, PECA1, GPIIA', PECAM 1, endoCAM, CD31/EndoCAM, platelet and endothelial cell adhesion molecule 1 |
| Protein Family | CD molecule |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 66.33 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T-cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrinαvβ3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.A DNA sequence encoding the extracellular domain (Met 1- Lys 61 ) of human CD31 (NP_433.3) precursor was expressed with the fused Fc region of human IgG1 at the C-terminus. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
