KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMH194 |
|---|---|
| Product Name | Recombinant Human CD39/ENTPD1 Protein, His Tag |
| Product Description | Recombinant Human CD39/ENTPD1 Protein, His Tag (KMH194) contains the human ENTPD1(Thr38-Val478) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | ENTPD1 |
| Uniprot ID | P49961 |
| Alias | CD39, SPG64, ATPDase, NTPDase 1, ENTPD1, ectonucleoside triphosphate diphosphohydrolase 1 |
| Protein Family | CD molecule |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 48.62 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | CD39, also known as ENTPD1, is a member of the GDA1/CD39 NTPase family. CD39 is weakly expressed on granulocytes while expressed highly on activated lymphoid cells. Human CD39 is found on most mature B cells, activated NK cells and activated T cells. In the nervous system, CD39 could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. It could also be implicated in the prevention of platelet aggregation and hydrolyzes ATP and ADP equally well. By hydrolyzing ATP and ADP, CD39 regulates vascular inflammation and thrombosis. It is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 transgenic mice exhibit impaired platelet aggregation, prolonged bleeding times, and resistance to systemic thromboembolism. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
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