KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMH2258 |
|---|---|
| Product Name | Recombinant Human PROM1 Protein |
| Alias | Prominin-1, AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4 |
| Size | 50ug, 100ug |
| Species | Human |
| Expression Host | E. coli |
| Source | A DNA sequence encoding the human PROM1(Gly508-Asn792) was fused with His Tag and expressed in E. coli cells. |
| Purity | ≥90% as determined by SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.5. |
| Background | CD133 antigen, also known as prominin-1, is a glycoprotein that in humans is encoded by the PROM1 gene. It is a member of pentaspan transmembrane glycoproteins, which specifically localize to cellular protrusions. When embedded in the cell membrane, the membrane topology of prominin-1 is such that the N-terminus extends into the extracellular space and the C-terminus resides in the intracellular compartment. The protein consists of five transmembrane segments, with the first and second segments and the third and fourth segments connected by intracellular loops while the second and third as well as fourth and fifth transmembrane segments are connected by extracellular loops. While the precise function of CD133 remains unknown, it has been proposed that it acts as an organizer of cell membrane topology. |
| Storage | Store the product at -20℃ to -80℃ for long term storage. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
