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Catalog Number | KMH316 |
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Product Name | Recombinant Human CD140B/PDGFRB Protein, His Tag |
Product Description | Recombinant Human CD140B/PDGFRB Protein, His Tag (KMH316) contains the human PDGFRB(Met1-Lys531) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | PDGFRB |
Uniprot ID | P09619 |
Alias | IMF1, KOGS, IBGC4, JTK12, PDGFR, PENTT, CD140B, PDGFR1, PDGFR 1, platelet derived growth factor receptor beta |
Protein Family | CD molecule |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 58.41 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | PDGFRβ (platelet-derived growth factor receptor) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRβ deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function. However, absence of PDGFRβ has no impact on major blood vessels and the heart. PDGFRβ expression and activity is elevated in several cancers and inhibition of PDGFRβ activity blocks progression of renal carcinoma in an animal model. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |