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Recombinant Human CD200 Protein, His Tag

Product Information
Catalog Number KMH364
Product Name Recombinant Human CD200 Protein, His Tag
Product Description Recombinant Human CD200 Protein, His Tag (KMH364) contains the human CD200(Met1-Gly232) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name CD200
Uniprot ID P41217
Alias MRC, MOX1, MOX2, OX 2, CD200 molecule
Protein Family CD molecule
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 25.52 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background CD2, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD2 is widely but not ubiquitously expressed. Its receptor (CD2R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD2. CD2 knockout mice are characterized by increased macrophage number and activation and are predisposed to autoimmune disorders. In T cells, CD2 functions as a costimulatory molecule independent of the CD28 pathway. Several viruses encode CD2 homologs which are expressed on infected cells during the lytic phase. Like CD2 itself, viral CD2 homologs also suppress myeloid cell activity, enabling increased viral propagation.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.