KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMH456 |
|---|---|
| Product Name | Recombinant Human CD309/KDR Protein, His Tag |
| Product Description | Recombinant Human CD309/KDR Protein, His Tag (KMH456) contains the human KDR(Met1-Lys327) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | KDR |
| Uniprot ID | P35968 |
| Alias | FLK1, CD309, VEGFR, VEGFR2, kinase insert domain receptor |
| Protein Family | CD molecule |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 35.97 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | KDR (or kinase insert domain receptor) is a growth factor receptor tyrosine kinase that was originally isolated from human endothelial cells where it plays a pivotal role in endothelial cell proliferation and differentiation. KDR and its mouse homolog Flk1 bind VEGF with high affinity and are implicated in the development of new blood vessels (angiogenesis). The expression levels of VEGF and KDR are highly correlated during the normal development of the ocular vasculature in humans (1). Induction of angiogenesis is a critical step in tumor progression, and inhibitors of KDR have been demonstrated both to induce tumor regression and reduce metastatic potential in preclinical models. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
