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Catalog Number | KMH504 |
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Product Name | Recombinant Human IKZF3 Protein, MYC/DDK Tag |
Product Description | Recombinant Human IKZF3 Protein, MYC/DDK Tag (KMH504) contains the human IKZF3(Met1-Lys509) was fused with the C-terminal MYC/DDK Tag and expressed in Mammalian cells. |
Molecular Name | IKZF3 |
Uniprot ID | Q9UKT9 |
Alias | AIO, AIOLOS, ZNFN1A3, IKAROS family zinc finger 3 |
Protein Family | Antibody drug target protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 55.99 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |