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Catalog Number | KMH508 |
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Product Name | Recombinant Human MET Protein, His Tag |
Product Description | Recombinant Human MET Protein, His Tag (KMH508) contains the human MET(Met1-Thr932) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | MET |
Uniprot ID | P08581 |
Alias | HGFR, AUTS9, RCCP2, c Met, DFNB97, MET proto oncogene, receptor tyrosine kinase |
Protein Family | Antibody drug target protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 102.52 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 5 kDa (alpha) and 145 kDa (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue. Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovariancancers and has been shown to be involved in tumor cell migration and invasion. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |