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Recombinant Human ECP/RNASE3 Protein, Fc Tag

Product Information
Catalog Number KMH568
Product Name Recombinant Human ECP/RNASE3 Protein, Fc Tag
Product Description Recombinant Human ECP/RNASE3 Protein, Fc Tag (KMH568) contains the human RNASE3(Met1-Ile160) was fused with the C-terminal Fc Tag and expressed in Mammalian cells.
Molecular Name RNASE3
Uniprot ID P12724
Alias ECP, RAF1, RNS3, ribonuclease A family member 3
Protein Family Other protein
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 44.53 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer Supplied as solution form in 1M Tris-HCl, 0.1M Glycine, pH7.5./Lyophilized from 1M Tris-HCl, 0.1M Glycine, pH7.5.
Purification Affinity Purification
Background Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.