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Catalog Number | KMH568 |
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Product Name | Recombinant Human ECP/RNASE3 Protein, Fc Tag |
Product Description | Recombinant Human ECP/RNASE3 Protein, Fc Tag (KMH568) contains the human RNASE3(Met1-Ile160) was fused with the C-terminal Fc Tag and expressed in Mammalian cells. |
Molecular Name | RNASE3 |
Uniprot ID | P12724 |
Alias | ECP, RAF1, RNS3, ribonuclease A family member 3 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 44.53 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | Supplied as solution form in 1M Tris-HCl, 0.1M Glycine, pH7.5./Lyophilized from 1M Tris-HCl, 0.1M Glycine, pH7.5. |
Purification | Affinity Purification |
Background | Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |