KMD Bioscience Co., Ltd.
400-621-6806
Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMH628 |
|---|---|
| Product Name | Recombinant Human Activin RIB/ALK-4/ACVR1B Protein, His Tag |
| Product Description | Recombinant Human Activin RIB/ALK-4/ACVR1B Protein, His Tag (KMH628) contains the human ACVR1B(Ser24-Glu126) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
| Molecular Name | ACVR1B |
| Uniprot ID | P36896 |
| Alias | ALK4, SKR2, ACTRIB, ACVRLK4, activin A receptor type 1B |
| Protein Family | Other protein |
| Size | 50ug, 100ug |
| Species | Human |
| Host | Mammalian cells |
| Molecular Weight | 11.33 kDa |
| Purity | ≥90% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
| Buffer | PBS |
| Purification | Affinity Purification |
| Background | Activin RIB, also known as ALK4, is a glycosylated type I receptor in the superfamily of TGF-β serine/threonine kinase receptors. Activin RIB associates with Activin RIIB to form a receptor complex for activin and inhibin molecules. These ligands bind to Activin RIIB which then associates with and phosphorylates the cytoplasmic domain of Activin RIB to initiate signal transduction.Within the ECD, human Activin RIB shares 93% and 95% aa sequence identity with mouse and rat Activin RIB, respectively. It shares 25% - 35% aa sequence identity with other human type I receptors Activin RIA, Activin RIC, BMPR-IA, BMPR-IB, and TGF-β R1. |
| Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
Technical Support：sales@kmdbiosci.com
