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Catalog Number | KMH650 |
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Product Name | Recombinant Human AKR1C4 Protein, His Tag |
Product Description | Recombinant Human AKR1C4 Protein, His Tag (KMH650) contains the human AKR1C4(Met1-Tyr323) was fused with the N-terminal His Tag and expressed in E. coli. |
Molecular Name | AKR1C4 |
Uniprot ID | P17516 |
Alias | C11, CDR, DD4, CHDR, DD 4, HAKRA, 3 alpha HSD, aldo keto reductase family 1 member C4 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | E. coli |
Molecular Weight | 35.53 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | Please contact our customer service for more information. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 1p15-p14. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |