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Catalog Number | KMH675 |
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Product Name | Recombinant Human ANTXR1 Protein, His Tag |
Product Description | Recombinant Human ANTXR1 Protein, His Tag (KMH675) contains the human ANTXR1(Glu33-Lys321) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
Molecular Name | ANTXR1 |
Uniprot ID | Q9H6X2 |
Alias | ATR, GAPO, TEM8, ANTXR cell adhesion molecule 1 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 31.79 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI). |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |