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Catalog Number | KMH741 |
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Product Name | Recombinant Human BID/BH3-interacting domain death agonist protein Protein, No Tag |
Product Description | Recombinant Human BID/BH3-interacting domain death agonist protein Protein, No Tag (KMH741) contains the human BID(Met1-Asp195) was fused without Tag and expressed in E. coli. |
Molecular Name | BID |
Uniprot ID | P55957 |
Alias | FP497, BH3 interacting domain death agonist |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | E. coli |
Molecular Weight | 21.45 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | Please contact our customer service for more information. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | BID is a BH3 interacting death domain that heterodimerizes with either agonist BAX or antagonist BCL2. BID is a member of the BCL-2 family of cell death regulators and is a mediator of mitochondrial damage induced by caspase-8 (CASP8). BID initiates apoptosis by binding to regulatory sites on prosurvival BCL2 proteins to directly neutralize their function. Multiple alternatively spliced transcript variants of BID have been found, but the full-length nature of some variants has not been defined. BID together with Cathepsins play an important role in the actions of Camptothecin on breast cancer cells. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |