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Catalog Number | KMH835 |
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Product Name | Recombinant Human CCL5/RANTES Protein, Fc & His Tag |
Product Description | Recombinant Human CCL5/RANTES Protein, Fc & His Tag (KMH835) contains the human CCL5(Ser24-Ser91) was fused with the C-terminal Fc and His Tag and expressed in Mammalian cells. |
Molecular Name | CCL5 |
Uniprot ID | P13501 |
Alias | SISd, eoCP, SCYA5, RANTES, TCP228, D17S136E, SIS delta, C C motif chemokine ligand 5 |
Protein Family | Other protein |
Size | 50ug, 100ug |
Species | Human |
Host | Mammalian cells |
Molecular Weight | 32.48 kDa |
Purity | ≥90% as determined by SDS-PAGE |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Cross-Reactivity | No cross-reactivity with other antigens or proteins. |
Buffer | PBS |
Purification | Affinity Purification |
Background | Chemokine (C-C motif) ligand 5 (CCL5) also known as RANTES is classified as a chemotactic cytokine or chemokine. It is encoded by the CCL5 gene in humans. CCL5 is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes into inflammatory sites which has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells. In addition, it also induces the proliferation and activation of certain natural-killer cells to form CHAK cells. Recombinant murine CCL5, a single non-glycosylated polypeptide, contains 68 amino acids and it shares 84% and 1% a.a. sequence identity with human and rat CCL5. |
Storage | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |