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Recombinant Human CNDP1 Protein, His Tag

Product Information
Catalog Number KMH896
Product Name Recombinant Human CNDP1 Protein, His Tag
Product Description Recombinant Human CNDP1 Protein, His Tag (KMH896) contains the human CNDP1(Pro28-His507) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Molecular Name CNDP1
Uniprot ID Q96KN2
Alias CN1, CPGL2, HsT2308, carnosine dipeptidase 1
Protein Family Other protein
Size 50ug, 100ug
Species Human
Host Mammalian cells
Molecular Weight 52.91 kDa
Purity ≥90% as determined by SDS-PAGE
Endotoxin < 1.0 EU per ug of the protein as determined by the LAL method.
Cross-Reactivity No cross-reactivity with other antigens or proteins.
Buffer PBS
Purification Affinity Purification
Background CNDP1, also known as beta-Ala-His dipeptidase, belongs to the peptidase M2A family. The shortest allelic form (CNDP1 Mannheim) was more common in the absence of nephropathy and was associated with lower serum carnosinase levels. Carnosine inhibited the increased production of fibronectin and collagen type VI in podocytes and the increased production of TGF-beta in mesangial cells. Diabetic patients with the CNDP1 Mannheim variant are less susceptible for nephropathy. Carnosine protects against the adverse effects of high glucose levels on renal cells.
Storage Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.