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| Catalog Number | KMP2544 |
|---|---|
| Product Name | Human LGALS3 Protein, His Tag |
| Product Description | The Human LGALS3 Protein(KMP2544) is produced in HEK293 Cells. The target gene encoding the human LGALS3 (NP_002297.2) (Ala2-Ile250) is expressed with a polyhistidine tag at the C-terminus. |
| Molecular Name | LGALS3 |
| Alias | Human LGALS3 Protein, His Tag, LGALS3 |
| Molecular Weight | 27.5 kDa |
| Species | Human |
| Size | 50ug, 100ug, 200ug |
| Host | HEK293 Cells |
| Purity | >95% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, 2mM Tcep, pH6.5 |
| Purification | Affinity purification |
| Background | LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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