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Human Meprin beta Protein, His Tag

Product Information
Catalog Number KMP2715
Product Name Human Meprin beta Protein, His Tag
Product Description The Human Meprin beta Protein(KMP2715) is produced in HEK293 Cells. The target gene encoding the human MEP1B (NP_005916.2) (Met1-Thr652) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name Meprin beta
Alias Human Meprin beta Protein, His Tag, Meprin beta
Molecular Weight 73 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in the kidney and intestine. Meprins are cell membrane, oligomeric metalloendopeptidases composed of two distinct but evolutionarily related subunits, alpha, and beta. MEP1A is mapped to the short arm of chromosome 6 by the use of radiation and somatic cell hybrids. More specifically, it is localized between the centromere and GSTA2 in 6p11-p12. MEP1B mapped to chromosome 18, by the use of somatic cell hybrids, in 18q12.2-q12.3, proximal to the TTR/PALB gene. Diseases associated with MEP1B include Powassan Encephalitis and Deafness, Autosomal Dominant 31.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.