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Catalog Number | KMP2715 |
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Product Name | Human Meprin beta Protein, His Tag |
Product Description | The Human Meprin beta Protein(KMP2715) is produced in HEK293 Cells. The target gene encoding the human MEP1B (NP_005916.2) (Met1-Thr652) is expressed with a polyhistidine tag at the C-terminus. |
Molecular Name | Meprin beta |
Alias | Human Meprin beta Protein, His Tag, Meprin beta |
Molecular Weight | 73 kDa |
Species | Human |
Size | 50ug, 100ug, 200ug |
Host | HEK293 Cells |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, pH7.4 |
Purification | Affinity purification |
Background | MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in the kidney and intestine. Meprins are cell membrane, oligomeric metalloendopeptidases composed of two distinct but evolutionarily related subunits, alpha, and beta. MEP1A is mapped to the short arm of chromosome 6 by the use of radiation and somatic cell hybrids. More specifically, it is localized between the centromere and GSTA2 in 6p11-p12. MEP1B mapped to chromosome 18, by the use of somatic cell hybrids, in 18q12.2-q12.3, proximal to the TTR/PALB gene. Diseases associated with MEP1B include Powassan Encephalitis and Deafness, Autosomal Dominant 31. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |