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Catalog Number | KMP2758 |
---|---|
Product Name | Human CXCL11 Protein |
Product Description | The Human CXCL11 Protein(KMP2758) is produced in E. coli. The target gene encoding the mature form of human CXCL11 (O14625) (Phe22-Phe94) is expressed with an initial Met. |
Molecular Name | CXCL11 |
Alias | Human CXCL11 Protein, CXCL11 |
Molecular Weight | 8.3 kDa |
Species | Human |
Size | 50ug, 100ug, 200ug |
Host | E. coli |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | 40% Acetonitrile, 1% TFA |
Purification | Affinity purification |
Background | I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |