Human Insulin Protein

Product Information

Catalog Number	KMP2835
Product Name	Human Insulin Protein
Product Description	The Human Insulin Protein(KMP2835) is produced in Yeast. The target gene encoding human insulin B chain (P01308)(Phe25-Lys53) and human insulin A chain (P01308)(Gly90-Asn110) is expressed with a linker AAK.
Molecular Name	Insulin
Alias	Human Insulin Protein, Insulin
Molecular Weight	7.1 kDa
Species	Human
Size	50ug, 100ug, 200ug
Host	Yeast
Purity	>95% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	PBS, pH7.4
Purification	Affinity purification
Background	INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

Cat#	Product Name	Species	Host	Applications	Size	Price