KMD Bioscience Co., Ltd.
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Service Line：+1-315-239-3085
Address：FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
| Catalog Number | KMP2858 |
|---|---|
| Product Name | Human IGF2BP2 Protein, His Tag, GST Tag |
| Product Description | The Human IGF2BP2 Protein(KMP2858) is produced in Insect Cells. The target gene encoding the human IGF2BP2 isoform 1 (Q9Y6M1-2) (Met 1-Lys 599) is fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
| Molecular Name | IGF2BP2 |
| Alias | Human IGF2BP2 Protein, His Tag, GST Tag, IGF2BP2 |
| Molecular Weight | 94 kDa |
| Species | Human |
| Size | 50ug, 100ug, 200ug |
| Host | Insect Cells |
| Purity | >75% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | 50mM Tris, 500mM NaCl, 0.5mM PMSF, 5mM Reduced Glutathione, pH8.0 |
| Purification | Affinity purification |
| Background | Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia, and semen (at protein level). It is also expressed in testicular cancer (at protein level). It is expressed weakly in the heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis, and pancreas. IGF2BP2 binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. This binding is isoform-specific. IGF2BP2 may regulate the translation of target mRNAs. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
FL-4, Building A5, International Enterprise Community, Tianjin, China
Email：info@kmdbioscience.com
Hot Line： +1-315-239-3085
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