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Human GBA Protein, His Tag

Product Information
Catalog Number KMP2966
Product Name Human GBA Protein, His Tag
Product Description The Human GBA Protein(KMP2966) is produced in HEK293 Cells. The target gene encoding the human GBA (NP_000148.2) (Ala40-Gln536) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name GBA
Alias Human GBA Protein, His Tag, GBA
Molecular Weight 57 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramidase 1) and GBA2 (glucocerebrosidase 2) enzymes that mediate glucosylsphingosine production and metabolism are attractive therapeutic targets for treating mutant GBA-associated PD.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.