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Catalog Number | KMP2974 |
---|---|
Product Name | Human PPARA Protein, His Tag |
Product Description | The Human PPARA Protein(KMP2974) is produced in E. coli. The target gene encoding the Human PPARA (Q07869) (Thr200-Tyr468) is expressed, with a polyhistidine tag at the N-terminus. |
Molecular Name | PPARA |
Alias | Human PPARA Protein, His Tag, PPARA |
Molecular Weight | 31.36 kDa |
Species | Human |
Size | 50ug, 100ug, 200ug |
Host | E. coli |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, 10% Glycerol, 0.5% SKL, pH8.0 |
Purification | Affinity purification |
Background | Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |