Contact Us

Service Line:+1-315-239-3085

Address:FL-4, Building A5, International Enterprise Community, Tianjin, China

Email:info@kmdbioscience.com

Online Inquery

  •   
  •   
  •   
  • Refresh

Human UNC5A Protein, hFc Tag

Product Information
Catalog Number KMP3064
Product Name Human UNC5A Protein, hFc Tag
Product Description The Human UNC5A Protein(KMP3064) is produced in HEK293 Cells. The target gene encoding the human UNC5A (NP_588610.2) (Met1-Tyr306) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name UNC5A
Alias Human UNC5A Protein, hFc Tag, UNC5A
Molecular Weight 58.3 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and regulating cell death in bladder cancer. Moreover, UNC5A is cumulatively downregulated by the unfolding protein response (UPR) at the transcriptional level in vitro and at the translational level both in vitro and in vivo. Also, UNC5A is a novel transcriptional target of p53 and plays a role in p53-dependent apoptosis.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.