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Human GLP1R Protein, His Tag, Avi Tag

Product Information
Catalog Number KMP3124
Product Name Human GLP1R Protein, His Tag, Avi Tag
Product Description The Human GLP1R Protein(KMP3124) is produced in HEK293 Cells. The target gene encoding the Human GLP1R (NP_002053.3) (Met1-Glu139) is expressed with a C-terminal polyhistidine tag followed by an Avi tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name GLP1R
Alias Human GLP1R Protein, His Tag, Avi Tag, GLP1R
Molecular Weight 16.79 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. GLP1R plays a critical role in mediating the biological actions of GLP1 in mammals and fish. The neuronal GLP1Rs mediate body weight and anorectic effects of liraglutide, but are not required for glucose-lowering effects. Glucagon-like peptide 1 receptor (GLP1R) signaling has been shown to have antipsychotic properties in animal models and to impact glucose-dependent insulin release, satiety, memory, and learning in man. Glucagon-like peptide-1 receptor (GLP1R) and glucose-dependent insulinotropic peptide receptor (GIPR) are their indirect drug targets.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.