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Catalog Number | KMP3150 |
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Product Name | Human TMIGD1 Protein, mFc Tag |
Product Description | The Human TMIGD1 Protein(KMP3150) is produced in HEK293 Cells. The target gene encoding the human TMIGD1 (NP_996663.1) (Met1-Pro220) is expressed with the Fc region of mouse IgG1 at the C-terminus. |
Molecular Name | TMIGD1 |
Alias | Human TMIGD1 Protein, mFc Tag, TMIGD1 |
Molecular Weight | 47.5 kDa |
Species | Human |
Size | 50ug, 100ug, 200ug |
Host | HEK293 Cells |
Purity | >95% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, pH7.4 |
Purification | Affinity purification |
Background | The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a novel candidate tumor suppressor gene and provides important insight into pathobiology of RCC that could lead to a better diagnosis and possible novel therapy for RCC. TMIGD1 controls cell migration, cell morphology, and protects renal epithelial cells from oxidative- and nutrient-deprivation-induced cell injury. TMIGD1 as a novel cell adhesion molecule expressed in kidney epithelial cells that protects kidney epithelial cells from oxidative cell injury to promote cell survival. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |