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Human TMIGD1 Protein, mFc Tag

Product Information
Catalog Number KMP3150
Product Name Human TMIGD1 Protein, mFc Tag
Product Description The Human TMIGD1 Protein(KMP3150) is produced in HEK293 Cells. The target gene encoding the human TMIGD1 (NP_996663.1) (Met1-Pro220) is expressed with the Fc region of mouse IgG1 at the C-terminus.
Molecular Name TMIGD1
Alias Human TMIGD1 Protein, mFc Tag, TMIGD1
Molecular Weight 47.5 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a novel candidate tumor suppressor gene and provides important insight into pathobiology of RCC that could lead to a better diagnosis and possible novel therapy for RCC. TMIGD1 controls cell migration, cell morphology, and protects renal epithelial cells from oxidative- and nutrient-deprivation-induced cell injury. TMIGD1 as a novel cell adhesion molecule expressed in kidney epithelial cells that protects kidney epithelial cells from oxidative cell injury to promote cell survival.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.