Human PSG1 Protein, His Tag

Product Information

Catalog Number	KMP3215
Product Name	Human PSG1 Protein, His Tag
Product Description	The Human PSG1 Protein(KMP3215) is produced in HEK293 Cells. The target gene encoding the human PSG1 (NP_001171754.1) (Met1-Pro419) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	PSG1
Alias	Human PSG1 Protein, His Tag, PSG1
Molecular Weight	44.9 kDa
Species	Human
Size	50ug, 100ug, 200ug
Host	HEK293 Cells
Purity	>95% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	PBS, pH7.4
Purification	Affinity purification
Background	Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human and murine PSG family have been shown to induce anti-inflammatory cytokines from monocytes and macrophages and to stimulate angiogenesis. Two distinct domains of PSG1 are involved in the regulation of TGF-beta1 and provide a mechanistic framework for how PSGs modulate the immunoregulatory environment at the maternal-fetal interface for successful pregnancy outcome.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

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