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Catalog Number | KMP3221 |
---|---|
Product Name | Human TPK1 Protein, His Tag |
Product Description | The Human TPK1 Protein(KMP3221) is produced in E. coli. The target gene encoding the human TPK1 (AAH68460.1) (Met1-Ser243) is expressed with a polyhistidine tag at the N-terminus. |
Molecular Name | TPK1 |
Alias | Human TPK1 Protein, His Tag, TPK1 |
Molecular Weight | 29.5 kDa |
Species | Human |
Size | 50ug, 100ug, 200ug |
Host | E. coli |
Purity | >90% as determined by SDS-PAGE |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Buffer | PBS, pH7.4 |
Purification | Affinity purification |
Background | Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans. |
Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Note | This product is for research use only. |