Human Claudin-6 Protein

Product Information

Catalog Number	KMP3389
Product Name	Human Claudin-6 Protein
Product Description	The Human Claudin-6 Protein(KMP3389) is produced in HEK293 Cells. The target gene encoding the human CLDN6 (NP_067018.2) (Met1-Val220) is expressed.
Molecular Name	Claudin-6
Alias	Human Claudin-6 Protein, Claudin-6
Molecular Weight	23.30 kDa
Species	Human
Size	50ug, 100ug, 200ug
Host	HEK293 Cells
Purity	>95% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	50mM HEPES, 150mM NaCl, 10% Trehalose, pH7.2
Purification	Affinity purification
Background	Claudin-6 (CLDN6) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and intracellular N and C tails. CLDN6 modulates the ion- and charge-specific permeability of the paracellular pathway in most epithelial tissues. It regulates the paracellular flux of cations in the kidney through forming heterotypic strands with other claudins and has a role in maintaining the lung epithelial barrier function. The CLDN6 gene is adjacent to another family member, CLDN9, on chromosome 16. Certain CLDN6-positive cancers, encompassing ovarian, endometrial, and testicular malignancies, have been shown to have their proliferation and invasiveness suppressed upon CLDN6 silencing.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

Cat#	Product Name	Species	Host	Size	Price
KMP3387	Human Claudin-6 Protein, His Tag, Avi Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP3388	Human Claudin-6 Protein, His Tag, Flag Tag	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry
KMP3390	Human Claudin-6 Protein	Human	HEK293 Cells	50ug, 100ug, 200ug	Inquiry