Contact Us

Service Line:+1-315-239-3085

Address:FL-4, Building A5, International Enterprise Community, Tianjin, China

Email:info@kmdbioscience.com

Online Inquery

  •   
  •   
  •   
  • Refresh

Human TL1A Protein, mFc Tag

Product Information
Catalog Number KMP3405
Product Name Human TL1A Protein, mFc Tag
Product Description The Human TL1A Protein(KMP3405) is produced in HEK293 Cells. The target gene encoding the human TNFSF15 (NP_005109.2) (Leu72-Leu251) is expressed with the Fc region of mouse IgG1 at the N-terminus.
Molecular Name TL1A
Alias Human TL1A Protein, mFc Tag, TL1A
Molecular Weight 47.1 kDa
Species Human
Size 50ug, 100ug, 200ug
Host HEK293 Cells
Purity >90% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Background TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. TL1A is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It mediates activation of NF-kappa-B. It also inhibits vascular endothelial growth and angiogenesis (in vitro). TL1A promotes activation of caspases and apoptosis. It is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.