Human GPRC5D-VLP Protein

Product Information

Catalog Number	KMP3461
Product Name	Human GPRC5D-VLP Protein
Product Description	The Human GPRC5D-VLP Protein(KMP3461) is produced in HEK293 Cells. The target gene encoding the human GPRC5D (Q9NZD1-1) (Met1-Val345) is expressed.
Molecular Name	GPRC5D-VLP
Alias	Human GPRC5D-VLP Protein, GPRC5D-VLP
Molecular Weight	38.80 kDa
Species	Human
Size	50ug, 100ug, 200ug
Host	HEK293 Cells
Purity	>95% as determined by SDS-PAGE
Endotoxin	<1.0 EU/ug determined by the LAL method
Buffer	50mM HEPES, 150mM NaCl, 10% Trehalose, pH7.2
Purification	Affinity purification
Background	Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells.
Storage	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note	This product is for research use only.

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