KMD Bioscience Co., Ltd.
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| Catalog Number | KMP3549 |
|---|---|
| Product Name | Human Integrin alpha 6 beta 4 Protein, Flag Tag, His Tag |
| Product Description | The Human Integrin alpha 6 beta 4 Protein(KMP3549) is produced in HEK293 Cells. The target gene encoding the extracellular domain (Met 1-Ser 1011) of human ITGA6 isoform alpha-6X1B (P23229-3) is fused with a flag tag at the C-terminus, constructed the plasmid 1 ; The target gene encoding the extracellular domain (Met 1-Ser 710) of human ITGB4 (CAA37656.1) is fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids are co-expressed and the heterodimer is purified |
| Molecular Name | Integrin alpha 6 beta 4 |
| Alias | Human Integrin alpha 6 beta 4 Protein, Flag Tag, His Tag, Integrin alpha 6 beta 4 |
| Molecular Weight | 196 kDa |
| Species | Human |
| Size | 50ug, 100ug, 200ug |
| Host | HEK293 Cells |
| Purity | >80% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Background | ITGB4 (Integrin Subunit Beta 4) is a Protein Coding gene. Diseases associated with ITGB4 include Epidermolysis Bullosa, Junctional 5B, With Pyloric Atresia and Epidermolysis Bullosa, Junctional 5A, Intermediate. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Integrin Pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and G protein-coupled receptor binding. An important paralog of this gene is ITGB1. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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