KMD Bioscience Co., Ltd.
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Email：info@kmdbioscience.com
| Catalog Number | KMP3664 |
|---|---|
| Product Name | Cynomolgus CD8 beta Protein, hFc Tag |
| Product Description | The Cynomolgus CD8 beta Protein(KMP3664) is produced in HEK293 Cells. A DNA sequence encoding the Cynomolgus CD8B (XP_005575417.1) (Met1-Pro170) is expressed with the Fc region of human IgG1 at the C-terminus. |
| Molecular Name | CD8 beta |
| Alias | CD8 beta Protein, Cynomolgus CD8 beta Protein, hFc Tag |
| Size | 50ug, 100ug, 200ug |
| Species | Cynomolgus |
| Host | HEK293 Cells |
| Purity | >90% as determined by SDS-PAGE |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Buffer | PBS, pH7.4 |
| Purification | Affinity purification |
| Molecular Weight | 43.88 kDa |
| Background | CD8B (CD8b molecule), also known as P37 and LEU2, contains 1 Ig-like V-type (immunoglobulin-like) domain. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. P37 gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. CD8 is thought to play a role in the process of T-cell mediated killing. |
| Storage | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Note | This product is for research use only. |
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