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Cynomolgus VEGF165 Protein, His Tag, Avi Tag

Product Information
Catalog Number KMP3798
Product Name Cynomolgus VEGF165 Protein, His Tag, Avi Tag
Product Description The Cynomolgus VEGF165 Protein(KMP3798) is produced in HEK293 Cells. A DNA sequence encoding the human, Cynomolgus VEGF165 (P15692-4) (Ala27-Arg191) is expressed with a C-terminal Avi tag followed by a polyhistidine tag. The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular Name VEGF165
Alias VEGF165 Protein, Cynomolgus VEGF165 Protein, His Tag, Avi Tag
Size 50ug, 100ug, 200ug
Species Cynomolgus
Host HEK293 Cells
Purity >95% as determined by SDS-PAGE
Endotoxin <1.0 EU/ug determined by the LAL method
Buffer PBS, pH7.4
Purification Affinity purification
Molecular Weight 23.1 kDa
Background Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.
Storage Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Note This product is for research use only.